"Albert Hofmann, who died on Tuesday aged 102, synthesized lysergic acid
diethylamide (LSD) in 1938 and became the first person in the world to
experience a full-blown acid trip." (Telegraph.co.uk)
Okay, I had two thoughts when I heard the news yesterday. First, anyone who had Dr. Hofmann in his celebrity death pool technically lost ground in the game. The way many of these pools work is on a point system. You generally get 100 points, minus the celebrity's age. That way Miley Cyrus, God forbid, would be worth 85 points but would be a much gutsier pick than, say, former First Lady Rosalynn Carter, who is on the exact flip side at 15 points. So if you had Hoffman, you owe 2.
Secondly, he was only 102. Imagine how long he might have lived if he'd stayed clean like his parents probably advised him to. This is why you shouldn't do drugs.
In case the letters LSD mean nothing to you, here is more from the rather interesting Telegraph obituary:
"Hofmann was working as a research chemist in the laboratory of the Sandoz
Company (now Novartis) in Basel, Switzerland, where he was involved in
studying the medicinal properties of plants. This eventually led to the study of the alkaloid compounds of ergot, a fungus which forms on rye.
Hofmann’s studies led to many new discoveries such as Hydergine, a medicament for improvement of circulation and cerebral function and Dihydergot, a circulation and blood pressure stabilizing medicine.
His interest in synthesising LSD was stimulated at first by the hope that it might also be useful as a circulatory and respiratory stimulant.
But when his molecule, known as LSD-25, was tested on animals, no interesting effects were observed, though the research notes recorded that the beasts became “restless” during narcosis. The substance was dismissed as of no interest and dropped from Sandoz’s research programme.
But five years later, acting on some intuition, Hofmann decided to resynthesise LSD. In his autobiography, LSD, My Problem Child (1979), he recalled that in the final stage of the synthesis, he was interrupted by some unusual sensations.
In a note to the laboratory’s director, he reported 'a remarkable restlessness, combined with a slight dizziness. At home I lay down and sank into a not unpleasant intoxicated-like condition, characterized by an extremely stimulated imagination.'
'In a dreamlike state, with eyes closed, I perceived an uninterrupted stream of fantastic pictures, extraordinary shapes with intense, kaleidoscopic play of colors. After some two hours this condition faded away.'
Hofmann concluded that he must have accidentally breathed in or ingested some
laboratory material and assumed LSD was the cause. To test the theory he waited until the next working day, Monday April 19 1943, and tried again, swallowing 0.25 of a milligram.
Forty minutes later, his laboratory journal recorded 'dizziness, feeling of anxiety, visual distortions, symptoms of paralysis, desire to laugh.'
Unable to write any more, he asked his assistant to take him home by bicycle. 'On the way home, my condition began to assume threatening forms.'
'Everything in my field of vision wavered and was distorted as if seen in a curved mirror. I also had the sensation of being unable to move from the spot. Nevertheless, my assistant later told me that we had traveled very rapidly.'
Back home, when a friendly neighbour brought round some milk, he perceived her as a 'malevolent, insidious witch wearing a lurid mask.' After six hours of highs and lows, the effects subsided.
Sandoz, keen to make a profit from Hofman’s discovery, gave the new substance the trade name Delysid and began sending samples out to psychiatric researchers.
By 1965 more than 2,000 papers had been published offering hope for a range of conditions from drug and alcohol addiction to mental illnesses of various sorts.
But the fact that it was cheap and easy to make left it open to abuse and from the late 1950s onwards, promoted by Dr. Timothy Leary and others, LSD became the recreational drug of choice for alienated western youth.
An outbreak of moral panic, combined with a number of accidents involving people jumping to their deaths off high buildings thinking they could fly, led governments around the world to ban LSD.
Research also showed that the drug taken in high doses and in inappropriate settings, often caused panic reactions. For certain individuals, a bad trip seemed to be the trigger for full-blown psychosis.
Hofmann was disappointed when his discovery was removed from commercial distribution. He remained convinced that the drug had the potential to counter the psychological problems induced by 'materialism, alienation from nature through industrialization and increasing urbanization, lack of satisfaction in professional employment in a mechanized, lifeless working world, ennui and purposelessness in wealthy, saturated society, and lack of a religious, nurturing, and meaningful philosophical foundation of life.'
Good times.
Not sure if anyone knows, but a song by the band Tool called Lost Keys (Blame Hofmann)is in reference to Albert. Lost Keys (Blame Hofmann) goes into a song called Rosetta Stoned, also by Tool which is pretty much about a guy having a bad lsd trip at Area51. Awesome song...if you don't have it get it.
Posted by: Raul | April 30, 2008 at 06:24 AM
Damn hippie...
Posted by: Vic Rattler | April 30, 2008 at 07:20 AM
Okay, you kow just a little too much about death pools...
But that info about the Dr. was quite interesting.
Posted by: Sketchbook by chris | April 30, 2008 at 10:09 AM
I'd like to ask the people using LSD to overcome the psychological problems induced by 'materialism, alienation from nature through industrialization and increasing urbanization, lack of satisfaction in professional employment in a mechanized, lifeless working world, ennui and purposelessness in wealthy, saturated society, and lack of a religious, nurturing, and meaningful philosophical foundation of life.' --- How's that working for you?
Posted by: brother john | April 30, 2008 at 11:25 AM
I love it when you can actually taste colors. It's rad.
Posted by: Edmund F | April 30, 2008 at 12:09 PM
I find it very interesting that most people blame the hippies for the proliferation of LSD. In fact the main champion was a Harvard Professor. Also, Ken Kesey, another proponate and activist was introduced to it by the Government. Of course Kesey and his merry pranksters were instumental in the birth of the hippie scene, but it was gobbled up by the media that definately had everything to do with the "fad" aspect and as the media will, focus on the more sensational aspects of it all. Like the grunge scene and any other group that gets co-opted by the commercial machine. Try reading Tom Wolfe's "Electric Kool-aid acid test" for an insiders view of the times from the inside- at the time.
Posted by: deejay | April 30, 2008 at 01:37 PM
I’ve used LSD quite a few times and noticed no noticeable side affects or blue fish eating the eyes of the proletariat underbelly pig snot – Wednesday of course…have a nice San Francisco treat….time to fly
Posted by: Ken | April 30, 2008 at 01:55 PM
Hey Bean,
Gene Gene the Dancing Machine is #107 in the death pool.
Posted by: Janet | April 30, 2008 at 05:27 PM
Is Gene Gene the Dancing Machine worth less points since his legs have already joined the hereafter? Is he pro-rated?
I submit that he should be.
Posted by: Vic Rattler | April 30, 2008 at 07:25 PM